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During vasculitis month we spoke to patients and carers to hear their real-world experiences with AAV first hand.1-3

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Patient Stories


John & Susan



Introduction to AAV

AAV is a rare, severe small vessel vasculitis that affects multiple organs and has a high acute mortality risk1

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Disease mechanism

The interaction between the activated alternative complement pathway, neutrophils and C5a is at the heart of vasculitic damage in AAV2

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Current therapies

Treatment has improved but treatment-related complications remain common3

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Patient experience

AAV is an emotional journey from the patient's perspective4-6

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Investigate AAV

Take the interactive challenge to assess your understanding of AAV. Fully interactive version available on desktop only

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References & footnotes