Our understanding of AAV is increasing

AAV (ANCA-associated vasculitis) is a group of progressive, rare, severe autoimmune diseases1,2

AAV can affect blood vessels in different parts of the body resulting in damage to vital organs such as the lungs, kidneys, nervous system, gastrointestinal system, skin, eyes, and heart.2

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Recent updates

Kidney week – American Society of Nephrology 2020 (virtual)

Renal disease during maintenance treatment in ANCA associated vasculitis (AAV) remains a problem and glucocorticoid use is high


Country differences exist in the treatment of ANCA associated vasculitis (AAV but high dose and prolonged glucocorticoid use is observed across Europe


German Congress of Rheumatology 2020

Maintenance treatment for ANCA-associated vasculitis (AAV) in real world practice in Germany - reality of vasculitis remission, relapse and burden of disease.


EULAR 2020

Maintenance treatment for ANCA-associated vasculitis in real world practise in Europe – reality of vasculitis remission and relapse and significant burden of disease.


Patterns of drug treatment for maintenance phase of ANCA-associated vasculitis (AAV) in real world practise in Europe – prolonged glucocorticoid use is common and various treatment regimes are used.



Significant burden of disease during maintenance treatment of ANCA-associated vasculitis (AAV) patients in real world practice in Europe.


Rare Revolution Magazine – Special edition

The latest edition of Rare Revolution Magazine is dedicated exclusively to ANCA-associated vasculitis. Rare Revolution is a digital magazine giving a voice to patients affected by RARE conditions and the charities that represent and support them – you can view the May edition here.

WCN 2020

Real world clinical outcomes in ANCA associated vasculitis (AAV) – unmet needs in achieving and sustaining remission and avoiding cumulative organ damage.

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Investigate AAV

Join the Rare Disease Investigation Team and put your expertise to the test in our interactive challenge. You’ll find it’s fully compatible with most desktop and mobile/tablet browsers (not for use on older versions of Internet Explorer or on Microsoft Edge).

Complete the challenge

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AAV Mechanism of Disease

See how the interaction between neutrophils and the alternative complement system are at the heart of the vasculitis process in AAV.

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Patient videos

View stories from Catherine, Jeremy, John & Susan and Shanali on the patient experience page.

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